About Olfactory receptor 4X2
Olfactory receptor 4X2 (OR4X2) is a protein
from Homo sapiens identified by UniProt accession
Q8NGF9, 303 residues long.
MolForge cross-references it against 0 known binders and
27 disease associations.
Target properties
| Protein name | Olfactory receptor 4X2 |
|---|
| UniProt accession | Q8NGF9 |
|---|
| Gene | OR4X2 |
|---|
| Organism | Homo sapiens |
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| Length | 303 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (27)
Diseases linked to this target (Open Targets).
- prostate adenocarcinoma · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- intraocular pressure measurement · score 0.14
- C-reactive protein measurement · score 0.12
- essential hypertension · score 0.08
- age at diagnosis · score 0.08
- glomerular filtration rate · score 0.07
- mean platelet volume · score 0.04
- lymphocyte count · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGF9-F1 | alphafold | PREDICTED | 84.99 | — |
Amino-acid sequence (303 residues)
MTEFIFLVLS PNQEVQRVCF VIFLFLYTAI VLGNFLIVLT VMTSRSLGSP MYFFLSYLSF MEICYSSATA PKLISDLLAE RKVISWWGCM AQLFFLHFFG GTEIFLLTVM AYDHYVAICK PLSYTTIMNW QVCTVLVGIA WVGGFMHSFA QILLIFHLLF CGPNVINHYF CDLVPLLKLA CSDTFLIGLL IVANGGTLSV ISFGVLLASY MVILLHLRTW SSEGWCKALS TCGSHFAVVI LFFGPCVFNS LRPSTTLPID KMVAVFYTVI TAILNPVIYS LRNAEMRKAM KRLWIRTLRL NEK
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