Olfactory receptor 8H1 (OR8H1)

About Olfactory receptor 8H1

Olfactory receptor 8H1 (OR8H1) is a protein from Homo sapiens identified by UniProt accession Q8NGG4, 311 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein name	Olfactory receptor 8H1
UniProt accession	Q8NGG4
Gene	OR8H1
Organism	Homo sapiens
Length	311 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (7)

Diseases linked to this target (Open Targets).

neuroblastoma · score 0.21
breast adenocarcinoma · score 0.18
leukocyte count · score 0.03
gastric carcinoma · score 0.01
neoplasm · score 0.00
neuropathy · score 0.00
Hyperlipidemia · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGG4-F1	alphafold	PREDICTED	89.72	—

Amino-acid sequence (311 residues)

MGRRNNTNVP DFILTGLSDS EEVQMALFIL FLLIYLITML GNVGMILIIR LDLQLHTPMY FFLTHLSFID LSYSTVITPK TLANLLTSNY ISFMGCFAQM FFFVFLGAAE CFLLSSMAYD RYVAICSPLR YPVIMSKRLC CALVTGPYVI SFINSFVNVV WMSRLHFCDS NVVRHFFCDT SPILALSCMD TYDIEIMIHI LAGSTLMVSL ITISASYVSI LSTILKINST SGKQKALSTC ASHLLGVTIF YGTMIFTYLK PRKSYSLGRD QVASVFYTIV IPMLNPLIYS LRNKEVKNAL IRVMQRRQDS R

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards