About Olfactory receptor 8K1
Olfactory receptor 8K1 (OR8K1) is a protein
from Homo sapiens identified by UniProt accession
Q8NGG5, 319 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Olfactory receptor 8K1 |
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| UniProt accession | Q8NGG5 |
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| Gene | OR8K1 |
|---|
| Organism | Homo sapiens |
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| Length | 319 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (14)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.18
- prostate adenocarcinoma · score 0.18
- pancreatic adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- 1,5 anhydroglucitol measurement · score 0.12
- appendicular lean mass · score 0.10
- leukocyte count · score 0.09
- age at menarche · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGG5-F1 | alphafold | PREDICTED | 88.26 | — |
Amino-acid sequence (319 residues)
MNHVVKHNHT AVTKVTEFIL MGITDNPGLQ APLFGLFLII YLVTVIGNLG MVILTYLDSK LHTPMYFFLR HLSITDLGYS TVIAPKMLVN FIVHKNTISY NWYATQLAFF EIFIISELFI LSAMAYDRYV AICKPLLYVI IMAEKVLWVL VIVPYLYSTF VSLFLTIKLF KLSFCGSNII SYFYCDCIPL MSILCSDTNE LELIILIFSG CNLLFSLSIV LISYMFILVA ILRMNSRKGR YKAFSTCSSH LTVVIMFYGT LLFIYLQPKS SHTLAIDKMA SVFYTLLIPM LNPLIYSLRN KEVKDALKRT LTNRFKIPI
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