About Olfactory receptor 8A1
Olfactory receptor 8A1 (OR8A1) is a protein
from Homo sapiens identified by UniProt accession
Q8NGG7, 326 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Olfactory receptor 8A1 |
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| UniProt accession | Q8NGG7 |
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| Gene | OR8A1 |
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| Organism | Homo sapiens |
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| Length | 326 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (7)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- acute myeloid leukemia · score 0.14
- schizophrenia · score 0.07
- breast carcinoma · score 0.01
- Ataxia-telangiectasia · score 0.01
- hepatocellular carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGG7-F1 | alphafold | PREDICTED | 87.01 | — |
Amino-acid sequence (326 residues)
MGFLSPMHPC RPPTQRRMAA GNHSTVTEFI LKGLTKRADL QLPLFLLFLG IYLVTIVGNL GMITLICLNS QLHTPMYYFL SNLSLMDLCY SSVITPKMLV NFVSEKNIIS YAGCMSQLYF FLVFVIAECY MLTVMAYDRY VAICHPLLYN IIMSHHTCLL LVAVVYAIGL IGSTIETGLM LKLPYCEHLI SHYFCDILPL MKLSCSSTYD VEMTVFFSAG FNIIVTSLTV LVSYTFILSS ILGISTTEGR SKAFSTCSSH LAAVGMFYGS TAFMYLKPST ISSLTQENVA SVFYTTVIPM LNPLIYSLRN KEVKAAVQKT LRGKLF
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