Olfactory receptor 2D3 (OR2D3)

About Olfactory receptor 2D3

Olfactory receptor 2D3 (OR2D3) is a protein from Homo sapiens identified by UniProt accession Q8NGH3, 330 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	Olfactory receptor 2D3
UniProt accession	Q8NGH3
Gene	OR2D3
Organism	Homo sapiens
Length	330 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

breast adenocarcinoma · score 0.18
blood protein measurement · score 0.02
COVID-19 · score 0.01
acute myocardial infarction · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGH3-F1	alphafold	PREDICTED	86.94	—

Amino-acid sequence (330 residues)

MCSFFLCQTG KQAKISMGEE NQTFVSKFIF LGLSQDLQTQ ILLFILFLII YLLTVLGNQL IIILIFLDSR LHTPMYFFLR NLSFADLCFS TSIVPQVLVH FLVKRKTISF YGCMTQIIVF LLVGCTECAL LAVMSYDRYV AVCKPLYYST IMTQRVCLWL SFRSWASGAL VSLVDTSFTF HLPYWGQNII NHYFCEPPAL LKLASIDTYS TEMAIFSMGV VILLAPVSLI LGSYWNIIST VIQMQSGEGR LKAFSTCGSH LIVVVLFYGS GIFTYMRPNS KTTKELDKMI SVFYTAVTPM LNPIIYSLRN KDVKGALRKL VGRKCFSHRQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards