About Olfactory receptor 52N4
Olfactory receptor 52N4 (OR52N4) is a protein
from Homo sapiens identified by UniProt accession
Q8NGI2, 321 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Olfactory receptor 52N4 |
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| UniProt accession | Q8NGI2 |
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| Gene | OR52N4 |
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| Organism | Homo sapiens |
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| Length | 321 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (9)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- head and neck malignant neoplasia · score 0.12
- gastric carcinoma · score 0.01
- COVID-19 · score 0.01
- cutaneous lupus erythematosus · score 0.01
- chronic myelogenous leukemia · score 0.00
- breast carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGI2-F1 | alphafold | PREDICTED | 89.60 | — |
Amino-acid sequence (321 residues)
MLTLNKTDLI PASFILNGVP GLEDTQLWIS FPFCSMYVVA MVGNCGLLYL IHYEDALHKP MYYFLAMLSF TDLVMCSSTI PKALCIFWFH LKDIGFDECL VQMFFTHTFT GMESGVLMLM ALDRYVAICY PLRYSTILTN PVIAKVGTAT FLRGVLLIIP FTFLTKLLPY CRGNILPHTY CDHMSVAKLS CGNVKVNAIY GLMVALLIWG FDILCITNSY TMILRAVVSL SSADARQKAF NTCTAHICAI VFSYTPAFFS FFSHRFGEHI IPPSCHIIVA NIYLLLPPTM NPIVYGVKTK QIRDCVIRIL SGSKDTKSYS M
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