About Olfactory receptor 52H1
Olfactory receptor 52H1 (OR52H1) is a protein
from Homo sapiens identified by UniProt accession
Q8NGJ2, 314 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | Olfactory receptor 52H1 |
|---|
| UniProt accession | Q8NGJ2 |
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| Gene | OR52H1 |
|---|
| Organism | Homo sapiens |
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| Length | 314 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (13)
Diseases linked to this target (Open Targets).
- medulloblastoma · score 0.21
- breast adenocarcinoma · score 0.18
- creatinine measurement · score 0.11
- glomerular filtration rate · score 0.11
- blood phosphate measurement · score 0.08
- cystatin C measurement · score 0.08
- uric acid measurement · score 0.08
- urate measurement · score 0.04
- colorectal adenocarcinoma · score 0.04
- breast carcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGJ2-F1 | alphafold | PREDICTED | 86.89 | — |
Amino-acid sequence (314 residues)
MIIFNLSSYN PGPFILVGIP GLEQFHVWIG IPFCIIYIVA VVGNCILLYL IVVEHSLHEP MFFFLSMLAM TDLILSTAGV PKALSIFWLG AREITFPGCL TQMFFLHYNF VLDSAILMAM AFDHYVAICS PLRYTTILTP KTIIKSAMGI SFRSFCIILP DVFLLTCLPF CRTRIIPHTY CEHIGVAQLA CADISINFWY GFCVPIMTVI SDVILIAVSY AHILCAVFGL PSQDACQKAL GTCGSHVCVI LMFYTPAFFS ILAHRFGHNV SRTFHIMFAN LYIVIPPALN PMVYGVKTKQ IRDKVILLFS KGTG
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