About Olfactory receptor 5L2
Olfactory receptor 5L2 (OR5L2) is a protein
from Homo sapiens identified by UniProt accession
Q8NGL0, 311 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Olfactory receptor 5L2 |
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| UniProt accession | Q8NGL0 |
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| Gene | OR5L2 |
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| Organism | Homo sapiens |
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| Length | 311 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (14)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- neuroblastoma · score 0.21
- chronic lymphocytic leukemia · score 0.18
- prostate adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- eosinophil count · score 0.03
- mean corpuscular volume · score 0.02
- gastric carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGL0-F1 | alphafold | PREDICTED | 89.41 | — |
Amino-acid sequence (311 residues)
MGKENCTTVA EFILLGLSDV PELRVCLFLL FLLIYGVTLL ANLGMTALIQ VSSRLHTPVY FFLSHLSFVD FCYSSIIVPK MLANIFNKDK AISFLGCMVQ FYLFCTCGVT EVFLLAVMAY DRFVAICNPL LYMVTMSQKL RVELTSCCYF CGTVCSLIHS SLALRILFYR SNVINHFFCD LPPLLSLACS DVTVNETLLF LVATLNESVT IMIILTSYLL ILTTILKIHS AESRHKAFST CASHLTAITV SHGTILYIYC RPSSGNSGDV DKVATVFYTV VIPMLNPLIY SLRNKDVNKA LRKVMGSKIH S
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