About Olfactory receptor 5D18
Olfactory receptor 5D18 (OR5D18) is a protein
from Homo sapiens identified by UniProt accession
Q8NGL1, 313 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | Olfactory receptor 5D18 |
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| UniProt accession | Q8NGL1 |
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| Gene | OR5D18 |
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| Organism | Homo sapiens |
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| Length | 313 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (13)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- chronic lymphocytic leukemia · score 0.18
- prostate adenocarcinoma · score 0.18
- pancreatic adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- multiple myeloma · score 0.16
- eosinophil count · score 0.16
- type 2 diabetes mellitus · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGL1-F1 | alphafold | PREDICTED | 88.46 | — |
Amino-acid sequence (313 residues)
MLLTDRNTSG TTFTLLGFSD YPELQVPLFL VFLAIYNVTV LGNIGLIVII KINPKLHTPM YFFLSQLSFV DFCYSSIIAP KMLVNLVVKD RTISFLGCVV QFFFFCTFVV TESFLLAVMA YDRFVAICNP LLYTVNMSQK LCVLLVVGSY AWGVSCSLEL TCSALKLCFH GFNTINHFFC EFSSLLSLSC SDTYINQWLL FFLATFNEIS TLLIVLTSYA FIVVTILKMR SVSGRRKAFS TCASHLTAIT IFHGTILFLY CVPNSKNSRH TVKVASVFYT VVIPMLNPLI YSLRNKDVKD TVTEILDTKV FSY
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