Olfactory receptor 5D14 (OR5D14)

About Olfactory receptor 5D14

Olfactory receptor 5D14 (OR5D14) is a protein from Homo sapiens identified by UniProt accession Q8NGL3, 314 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Olfactory receptor 5D14
UniProt accession	Q8NGL3
Gene	OR5D14
Organism	Homo sapiens
Length	314 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

serum alanine aminotransferase measurement · score 0.28
neuroblastoma · score 0.21
pulse pressure measurement · score 0.21
clear cell renal carcinoma · score 0.18
low grade glioma · score 0.18
ovarian cancer · score 0.18
breast adenocarcinoma · score 0.18
systolic blood pressure · score 0.17
eosinophil count · score 0.16
aspartate aminotransferase measurement · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGL3-F1	alphafold	PREDICTED	89.27	—

Amino-acid sequence (314 residues)

MMMVLRNLSM EPTFALLGFT DYPKLQIPLF LVFLLMYVIT VVGNLGMIII IKINPKFHTP MYFFLSHLSF VDFCYSSIVT PKLLENLVMA DKSIFYFSCM MQYFLSCTAV VTESFLLAVM AYDRFVAICN PLLYTVAMSQ RLCALLVAGS YLWGMFGPLV LLCYALRLNF SGPNVINHFF CEYTALISVS GSDILIPHLL LFSFATFNEM CTLLIILTSY VFIFVTVLKI RSVSGRHKAF STWASHLTSI TIFHGTILFL YCVPNSKNSR QTVKVASVFY TVVNPMLNPL IYSLRNKDVK DAFWKLIHTQ VPFH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards