About Olfactory receptor 4C16
Olfactory receptor 4C16 (OR4C16) is a protein
from Homo sapiens identified by UniProt accession
Q8NGL9, 310 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Olfactory receptor 4C16 |
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| UniProt accession | Q8NGL9 |
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| Gene | OR4C16 |
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| Organism | Homo sapiens |
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| Length | 310 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (29)
Diseases linked to this target (Open Targets).
- prostate adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- hepatocellular carcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- chronic lymphocytic leukemia · score 0.18
- breast adenocarcinoma · score 0.18
- blood coagulation disease · score 0.08
- pappalysin‐1 measurement · score 0.07
- lymphocyte count · score 0.06
- cardiovascular disease · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGL9-F1 | alphafold | PREDICTED | 86.38 | — |
Amino-acid sequence (310 residues)
MQLNNNVTEF ILLGLTQDPF WKKIVFVIFL RLYLGTLLGN LLIIISVKTS QALKNPMFFF LFYLSLSDTC LSTSITPRMI VDALLKKTTI SFSECMIQVF SSHVFGCLEI FILILTAVDR YVDICKPLHY MTIISQWVCG VLMAVAWVGS CVHSLVQIFL ALSLPFCGPN VINHCFCDLQ PLLKQACSET YVVNLLLVSN SGAICAVSYV MLIFSYVIFL HSLRNHSAEV IKKALSTCVS HIIVVILFFG PCIFMYTCLA TVFPMDKMIA VFYTVGTSFL NPVIYTLKNT EVKSAMRKLW SKKLITDDKR
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