About Olfactory receptor 6M1
Olfactory receptor 6M1 (OR6M1) is a protein
from Homo sapiens identified by UniProt accession
Q8NGM8, 313 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Olfactory receptor 6M1 |
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| UniProt accession | Q8NGM8 |
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| Gene | OR6M1 |
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| Organism | Homo sapiens |
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| Length | 313 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (11)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- pancreatic adenocarcinoma · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- colorectal adenocarcinoma · score 0.05
- non-small cell lung carcinoma · score 0.03
- bone density · score 0.03
- urate measurement · score 0.03
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGM8-F1 | alphafold | PREDICTED | 91.04 | — |
Amino-acid sequence (313 residues)
MGNWSTVTEI TLIAFPALLE IRISLFVVLV VTYTLTATGN ITIISLIWID HRLQTPMYFF LSNLSFLDIL YTTVITPKLL ACLLGEEKTI SFAGCMIQTY FYFFLGTVEF ILLAVMSFDR YMAICDPLHY TVIMNSRACL LLVLGCWVGA FLSVLFPTIV VTRLPYCRKE INHFFCDIAP LLQVACINTH LIEKINFLLS ALVILSSLAF TTGSYVYIIS TILRIPSTQG RQKAFSTCAS HITVVSIAHG SNIFVYVRPN QNSSLDYDKV AAVLITVVTP LLNPFIYSLR NEKVQEVLRE TVNRIMTLIQ RKT
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