About Olfactory receptor 8D4
Olfactory receptor 8D4 (OR8D4) is a protein
from Homo sapiens identified by UniProt accession
Q8NGM9, 314 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Olfactory receptor 8D4 |
|---|
| UniProt accession | Q8NGM9 |
|---|
| Gene | OR8D4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 314 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- clear cell renal carcinoma · score 0.18
- hepatocellular carcinoma · score 0.18
- prostate adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- breast carcinoma · score 0.04
- urate measurement · score 0.03
- bone density · score 0.03
- gastric carcinoma · score 0.01
- Systemic lupus erythematosus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGM9-F1 | alphafold | PREDICTED | 90.40 | — |
Amino-acid sequence (314 residues)
MGVKNHSTVT EFLLSGLTEQ AELQLPLFCL FLGIYTVTVV GNLSMISIIR LNRQLHTPMY YFLSSLSFLD FCYSSVITPK MLSGFLCRDR SISYSGCMIQ LFFFCVCVIS ECYMLAAMAC DRYVAICSPL LYRVIMSPRV CSLLVAAVFS VGFTDAVIHG GCILRLSFCG SNIIKHYFCD IVPLIKLSCS STYIDELLIF VIGGFNMVAT SLTIIISYAF ILTSILRIHS KKGRCKAFST CSSHLTAVLM FYGSLMSMYL KPASSSSLTQ EKVSSVFYTT VILMLNPLIY SLRNNEVRNA LMKLLRRKIS LSPG
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