Olfactory receptor 8J1 (OR8J1)

About Olfactory receptor 8J1

Olfactory receptor 8J1 (OR8J1) is a protein from Homo sapiens identified by UniProt accession Q8NGP2, 316 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	Olfactory receptor 8J1
UniProt accession	Q8NGP2
Gene	OR8J1
Organism	Homo sapiens
Length	316 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (12)

Diseases linked to this target (Open Targets).

ovarian cancer · score 0.18
prostate adenocarcinoma · score 0.18
multiple myeloma · score 0.16
leukocyte count · score 0.05
1,5 anhydroglucitol measurement · score 0.05
appendicular lean mass · score 0.04
pancreatic adenocarcinoma · score 0.04
high density lipoprotein cholesterol measurement · score 0.02
C-reactive protein measurement · score 0.02
primary ovarian insufficiency · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGP2-F1	alphafold	PREDICTED	89.33	—

Amino-acid sequence (316 residues)

MAPENFTRVT EFILTGVSSC PELQIPLFLV FLVLYGLTMA GNLGIITLTS VDSRLQTPMY FFLQHLALIN LGNSTVIAPK MLINFLVKKK TTSFYECATQ LGGFLFFIVS EVIMLALMAY DRYVAICNPL LYMVVVSRRL CLLLVSLTYL YGFSTAIVVS SYVFSVSYCS SNIINHFYCD NVPLLALSCS DTYLPETVVF ISAATNVVGS LIIVLVSYFN IVLSILKICS SEGRKKAFST CASHMMAVTI FYGTLLFMYV QPRSNHSLDT DDKMASVFYT LVIPMLNPLI YSLRNKDVKT ALQRFMTNLC YSFKTM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards