About Olfactory receptor 5M3
Olfactory receptor 5M3 (OR5M3) is a protein
from Homo sapiens identified by UniProt accession
Q8NGP4, 307 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Olfactory receptor 5M3 |
|---|
| UniProt accession | Q8NGP4 |
|---|
| Gene | OR5M3 |
|---|
| Organism | Homo sapiens |
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| Length | 307 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (14)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- thyroid gland adenocarcinoma · score 0.22
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- hypertension · score 0.06
- blood pressure · score 0.06
- high density lipoprotein cholesterol measurement · score 0.03
- coffee consumption measurement · score 0.03
- systolic blood pressure · score 0.02
- leukocyte count · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGP4-F1 | alphafold | PREDICTED | 92.27 | — |
Amino-acid sequence (307 residues)
MLNFTDVTEF ILLGLTSRRE WQVLFFIIFL VVYIITMVGN IGMMVLIKVS PQLNNPMYFF LSHLSFVDVW FSSNVTPKML ENLLSDKKTI TYAGCLVQCF FFIALVHVEI FILAAMAFDR YMAIGNPLLY GSKMSRVVCI RLITFPYIYG FLTSLAATLW TYGLYFCGKI EINHFYCADP PLIKMACAGT FVKEYTMIIL AGINFTYSLT VIIISYLFIL IAILRMRSAE GRQKAFSTCG SHLTAVIIFY GTLIFMYLRR PTEESVEQGK MVAVFYTTVI PMLNPMIYSL RNKDVKKAMM KVISRSC
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