About Olfactory receptor 5M1
Olfactory receptor 5M1 (OR5M1) is a protein
from Homo sapiens identified by UniProt accession
Q8NGP8, 315 residues long.
MolForge cross-references it against 0 known binders and
19 disease associations.
Target properties
| Protein name | Olfactory receptor 5M1 |
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| UniProt accession | Q8NGP8 |
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| Gene | OR5M1 |
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| Organism | Homo sapiens |
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| Length | 315 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (19)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- hepatocellular carcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- prostate adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- acute myeloid leukemia · score 0.14
- systolic blood pressure · score 0.04
- unipolar depression · score 0.03
- smoking behaviour measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGP8-F1 | alphafold | PREDICTED | 89.78 | — |
Amino-acid sequence (315 residues)
MFSPNHTIVT EFILLGLTDD PVLEKILFGV FLAIYLITLA GNLCMILLIR TNSHLQTPMY FFLGHLSFVD ICYSSNVTPN MLHNFLSEQK TISYAGCFTQ CLLFIALVIT EFYILASMAL DRYVAICSPL HYSSRMSKNI CVCLVTIPYM YGFLSGFSQS LLTFHLSFCG SLEINHFYCA DPPLIMLACS DTRVKKMAMF VVAGFNLSSS LFIILLSYLF IFAAIFRIRS AEGRHKAFST CASHLTIVTL FYGTLFCMYV RPPSEKSVEE SKITAVFYTF LSPMLNPLIY SLRNTDVILA MQQMIRGKSF HKIAV
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