About Olfactory receptor 1L4
Olfactory receptor 1L4 (OR1L4) is a protein
from Homo sapiens identified by UniProt accession
Q8NGR5, 311 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Olfactory receptor 1L4 |
|---|
| UniProt accession | Q8NGR5 |
|---|
| Gene | OR1L4 |
|---|
| Organism | Homo sapiens |
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| Length | 311 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- clear cell renal carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- lymphocyte percentage of leukocytes · score 0.02
- acute myeloid leukemia · score 0.01
- mixed germ cell tumor · score 0.00
- embryonal carcinoma · score 0.00
- diabetes mellitus · score 0.00
- asthma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGR5-F1 | alphafold | PREDICTED | 88.80 | — |
Amino-acid sequence (311 residues)
METKNYSSST SGFILLGLSS NPKLQKPLFA IFLIMYLLTA VGNVLIILAI YSDPRLHTPM YFFLSNLSFM DICFTTVIVP KMLVNFLSET KIISYVGCLI QMYFFMAFGN TDSYLLASMA IDRLVAICNP LHYDVVMKPW HCLLMLLGSC SISHLHSLFR VLLMSRLSFC ASHIIKHFFC DTQPVLKLSC SDTSSSQMVV MTETLAVIVT PFLCTIFSYL QIIVTVLRIP SAAGKWKAFS TCGSHLTVVV LFYGSVIYVY FRPLSMYSVM KGRVATVMYT VVTPMLNPFI YSLRNKDMKR GLKKLRHRIY S
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