About Olfactory receptor 1L8
Olfactory receptor 1L8 (OR1L8) is a protein
from Homo sapiens identified by UniProt accession
Q8NGR8, 309 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Olfactory receptor 1L8 |
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| UniProt accession | Q8NGR8 |
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| Gene | OR1L8 |
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| Organism | Homo sapiens |
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| Length | 309 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- chronic lymphocytic leukemia · score 0.18
- clear cell renal carcinoma · score 0.18
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- lymphocyte percentage of leukocytes · score 0.03
- acute myeloid leukemia · score 0.01
- small cell lung carcinoma · score 0.01
- prostate carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGR8-F1 | alphafold | PREDICTED | 86.51 | — |
Amino-acid sequence (309 residues)
MERINHTSSV SEFILLGLSS RPEDQKTLFV LFLIVYLVTI TGNLLIILAI RFNPHLQTPM YFFLSFLSLT DICFTTSVVP KMLMNFLSEK KTISYAGCLT QMYFLYALGN SDSCLLAVMA FDRYVAVCDP FHYVTTMSHH HCVLLVAFSC SFPHLHSLLH TLLLNRLTFC DSNVIHHFLC DLSPVLKLSC SSIFVNEIVQ MTEAPIVLVT RFLCIAFSYI RILTTVLKIP STSGKRKAFS TCGFYLTVVT LFYGSIFCVY LQPPSTYAVK DHVATIVYTV LSSMLNPFIY SLRNKDLKQG LRKLMSKRS
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