About Olfactory receptor 1J1
Olfactory receptor 1J1 (OR1J1) is a protein
from Homo sapiens identified by UniProt accession
Q8NGS3, 322 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Olfactory receptor 1J1 |
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| UniProt accession | Q8NGS3 |
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| Gene | OR1J1 |
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| Organism | Homo sapiens |
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| Length | 322 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (7)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- neuroblastoma · score 0.21
- prostate adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- lymphocyte percentage of leukocytes · score 0.03
- acute myeloid leukemia · score 0.01
- small cell lung carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGS3-F1 | alphafold | PREDICTED | 87.72 | — |
Amino-acid sequence (322 residues)
MSPENQSSVS EFLLLGLPIR PEQQAVFFAL FLGMYLTTVL GNLLIMLLIQ LDSHLHTPMY FFLSHLALTD ISFSSVTVPK MLMNMQTQHL AVFYKGCISQ TYFFIFFADL DSFLITSMAY DRYVAICHPL HYATIMTQSQ CVMLVAGSWV IACACALLHT LLLAQLSFCA DHIIPHYFCD LGALLKLSCS DTSLNQLAIF TAALTAIMLP FLCILVSYGH IGVTILQIPS TKGICKALST CGSHLSVVTI YYRTIIGLYF LPPSSNTNDK NIIASVIYTA VTPMLNPFIY SLRNKDIKGA LRKLLSRSGA VAHACNLNTL GG
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