About Olfactory receptor 2A12
Olfactory receptor 2A12 (OR2A12) is a protein
from Homo sapiens identified by UniProt accession
Q8NGT7, 310 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Olfactory receptor 2A12 |
|---|
| UniProt accession | Q8NGT7 |
|---|
| Gene | OR2A12 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 310 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- low grade glioma · score 0.18
- clear cell renal carcinoma · score 0.18
- hepatocellular carcinoma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- multiple myeloma · score 0.16
- COVID-19 · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGT7-F1 | alphafold | PREDICTED | 86.55 | — |
Amino-acid sequence (310 residues)
MESNQTWITE VILLGFQVDP ALELFLFGFF LLFYSLTLMG NGIILGLIYL DSRLHTPMYV FLSHLAIVDM SYASSTVPKM LANLVMHKKV ISFAPCILQT FLYLAFAITE CLILVMMCYD RYVAICHPLQ YTLIMNWRVC TVLASTCWIF SFLLALVHIT LILRLPFCGP QKINHFFCQI MSVFKLACAD TRLNQVVLFA GSAFILVGPL CLVLVSYLHI LVAILRIQSG EGRRKAFSTC SSHLCVVGLF FGSAIVMYMA PKSSHSQERR KILSLFYSLF NPILNPLIYS LRNAEVKGAL KRVLWKQRSM
Explore Olfactory receptor 2A12 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets