Olfactory receptor 11L1 (OR11L1)

About Olfactory receptor 11L1

Olfactory receptor 11L1 (OR11L1) is a protein from Homo sapiens identified by UniProt accession Q8NGX0, 322 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Olfactory receptor 11L1
UniProt accession	Q8NGX0
Gene	OR11L1
Organism	Homo sapiens
Length	322 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

platelet component distribution width · score 0.24
neuroblastoma · score 0.21
prostate adenocarcinoma · score 0.18
clear cell renal carcinoma · score 0.18
low grade glioma · score 0.18
ovarian cancer · score 0.18
breast adenocarcinoma · score 0.18
reticulocyte measurement · score 0.14
platelet count · score 0.03
Immature Reticulocyte Fraction Measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGX0-F1	alphafold	PREDICTED	88.51	—

Amino-acid sequence (322 residues)

MEPQNTSTVT NFQLLGFQNL LEWQALLFVI FLLIYCLTII GNVVIITVVS QGLRLHSPMY MFLQHLSFLE VWYTSTTVPL LLANLLSWGQ AISFSACMAQ LYFFVFLGAT ECFLLAFMAY DRYLAICSPL RYPFLMHRGL CARLVVVSWC TGVSTGFLPS LMISRLDFCG RNQINHFFCD LPPLMQLSCS RVYITEVTIF ILSIAVLCIC FFLTLGPYVF IVSSILRIPS TSGRRKTFST CGSHLAVVTL YYGTMISMYV CPSPHLLPEI NKIISVFYTV VTPLLNPVIY SLRNKDFKEA VRKVMRRKCG ILWSTSKRKF LY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards