About Olfactory receptor 10T2
Olfactory receptor 10T2 (OR10T2) is a protein
from Homo sapiens identified by UniProt accession
Q8NGX3, 314 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Olfactory receptor 10T2 |
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| UniProt accession | Q8NGX3 |
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| Gene | OR10T2 |
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| Organism | Homo sapiens |
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| Length | 314 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (11)
Diseases linked to this target (Open Targets).
- adolescent idiopathic scoliosis · score 0.18
- clear cell renal carcinoma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- mean corpuscular volume · score 0.13
- hematological measurement · score 0.13
- mean reticulocyte volume · score 0.13
- sphingomyelin measurement · score 0.08
- QRS duration · score 0.05
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGX3-F1 | alphafold | PREDICTED | 84.86 | — |
Amino-acid sequence (314 residues)
MRGFNKTTVV TQFILVGFSS LGELQLLLFV IFLLLYLTIL VANVTIMAVI RFSWTLHTPM YGFLFILSFS ESCYTFVIIP QLLVHLLSDT KTISFMACAT QLFFFLGFAC TNCLLIAVMG YDRYVAICHP LRYTLIINKR LGLELISLSG ATGFFIALVA TNLICDMRFC GPNRVNHYFC DMAPVIKLAC TDTHVKELAL FSLSILVIMV PFLLILISYG FIVNTILKIP SAEGKKAFVT CASHLTVVFV HYGCASIIYL RPKSKSASDK DQLVAVTYTV VTPLLNPLVY SLRNKEVKTA LKRVLGMPVA TKMS
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