About Olfactory receptor 6K2
Olfactory receptor 6K2 (OR6K2) is a protein
from Homo sapiens identified by UniProt accession
Q8NGY2, 324 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Olfactory receptor 6K2 |
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| UniProt accession | Q8NGY2 |
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| Gene | OR6K2 |
|---|
| Organism | Homo sapiens |
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| Length | 324 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (16)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.35
- hematological measurement · score 0.23
- thyroid gland adenocarcinoma · score 0.22
- neuroblastoma · score 0.21
- clear cell renal carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- mean reticulocyte volume · score 0.14
- Familial prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGY2-F1 | alphafold | PREDICTED | 88.16 | — |
Amino-acid sequence (324 residues)
MESPNRTTIQ EFIFSAFPYS WVKSVVCFVP LLFIYAFIVV GNLVIITVVQ LNTHLHTPMY TFISALSFLE IWYTTATIPK MLSSLLSERS ISFNGCLLQM YFFHSTGICE VCLLTVMAFD HYLAICSPLH YPSIMTPKLC TQLTLSCCVC GFITPLPEIA WISTLPFCGS NHLEHIFCDF LPVLRLACTD TRAIVMIQVV DVIHAVEIIT AVMLIFMSYD GIVAVILRIH SAGGRRTAFS TCVSHFIVFS LFFGSVTLMY LRFSATYSLF WDIAIALAFA VLSPFFNPII YSLRNKEIKE AIKKHIGQAK IFFSVRPGTS SKIF
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