Olfactory receptor 14K1 (OR14K1)

About Olfactory receptor 14K1

Olfactory receptor 14K1 (OR14K1) is a protein from Homo sapiens identified by UniProt accession Q8NGZ2, 314 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Olfactory receptor 14K1
UniProt accession	Q8NGZ2
Gene	OR14K1
Organism	Homo sapiens
Length	314 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

ovarian cancer · score 0.18
breast adenocarcinoma · score 0.18
diffuse large B-cell lymphoma · score 0.10
reticulocyte count · score 0.04
diabetes mellitus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGZ2-F1	alphafold	PREDICTED	83.49	—

Amino-acid sequence (314 residues)

MTNQTQMMEF LLVRFTENWV LLRLHALLFS LIYLTAVLMN LVIILLMILD HRLHMAMYFF LRHLSFLDLC LISATVPKSI LNSVASTDSI SFLGCVLQLF LVVLLAGSEI GILTAMSYDR YAAICCPLHC EAVMSRGLCV QLMALSWLNR GALGLLYTAG TFSLNFYGSD ELHQFFCDVP ALLKLTCSKE HAIISVSVAI GVCYAFSCLV CIVVSYVYIF SAVLRISQRQ RQSKAFSNCV PHLIVVTVFL VTGAVAYLKP GSDAPSILDL LVSVFYSVAP PTLNPVIYCL KNKDIKSALS KVLWNVRSSG VMKR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards