About Olfactory receptor 2T3
Olfactory receptor 2T3 (OR2T3) is a protein
from Homo sapiens identified by UniProt accession
Q8NH03, 318 residues long.
MolForge cross-references it against 0 known binders and
6 disease associations.
Target properties
| Protein name | Olfactory receptor 2T3 |
|---|
| UniProt accession | Q8NH03 |
|---|
| Gene | OR2T3 |
|---|
| Organism | Homo sapiens |
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| Length | 318 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (6)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- neuroblastoma · score 0.21
- prostate adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- protein measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NH03-F1 | alphafold | PREDICTED | 88.18 | — |
Amino-acid sequence (318 residues)
MCSGNQTSQN QTASTDFTLT GLFAESKHAA LLYTVTFLLF LMALTGNALL ILLIHSEPRL HTPMYFFISQ LALMDLMYLC VTVPKMLVGQ VTGDDTISPS GCGIQMFFYL TLAGAEVFLL AAMAYDRYAA VCRPLHYPLL MNQRVCQLLV SACWVLGMVD GLLLTPITMS FPFCQSRKIL SFFCETPALL KLSCSDVSLY KTLMYLCCIL MLLAPIMVIS SSYTLILHLI HRMNSAAGHR KALATCSSHM IIVLLLFGAS FYTYMLPSSY HTAEQDMMVS AFYTIFTPVL NPLIYSLRNK DVTRALRSMM QSRMNQEK
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