About Olfactory receptor 8U1
Olfactory receptor 8U1 (OR8U1) is a protein
from Homo sapiens identified by UniProt accession
Q8NH10, 309 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Olfactory receptor 8U1 |
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| UniProt accession | Q8NH10 |
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| Gene | OR8U1 |
|---|
| Organism | Homo sapiens |
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| Length | 309 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (7)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.19
- clear cell renal carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- leukocyte count · score 0.03
- high density lipoprotein cholesterol measurement · score 0.02
- gastric carcinoma · score 0.01
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NH10-F1 | alphafold | PREDICTED | 89.82 | — |
Amino-acid sequence (309 residues)
MAHINCTQAT EFILVGLTDH QELKMPLFVL FLSIYLFTVV GNLGLILLIR ADTSLNTPMY FFLSNLAFVD FCYSSVITPK MLGNFLYKQN VISFDACATQ LGCFLTFMIS ESLLLASMAY DRYVAICNPL LYMVVMTPGI CIQLVAVPYS YSFLMALFHT ILTFRLSYCH SNIVNHFYCD DMPLLRLTCS DTRFKQLWIF ACAGIMFISS LLIVFVSYMF IISAILRMHS AEGRQKAFST CGSHMLAVTI FYGTLIFMYL QPSSSHALDT DKMASVFYTV IIPMLNPLIY SLQNKEVKEA LKKIIINKN
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