About Olfactory receptor 4C3
Olfactory receptor 4C3 (OR4C3) is a protein
from Homo sapiens identified by UniProt accession
Q8NH37, 302 residues long.
MolForge cross-references it against 0 known binders and
15 disease associations.
Target properties
| Protein name | Olfactory receptor 4C3 |
|---|
| UniProt accession | Q8NH37 |
|---|
| Gene | OR4C3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 302 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (15)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- neuroblastoma · score 0.21
- clear cell renal carcinoma · score 0.18
- prostate adenocarcinoma · score 0.18
- erythrocyte count · score 0.05
- cardiac arrhythmia · score 0.04
- chronic obstructive pulmonary disease · score 0.03
- high density lipoprotein cholesterol measurement · score 0.03
- IGF-1 measurement · score 0.02
- glomerular filtration rate · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NH37-F1 | alphafold | PREDICTED | 89.80 | — |
Amino-acid sequence (302 residues)
MDIPQNITEF FMLGLSQNSE VQRVLFVVFL LIYVVTVCGN MLIVVTITSS PTLASPVYFF LANLSFIDTF YSSSMAPKLI ADSLYEGRTI SYECCMAQLF GAHFLGGVEI ILLTVMAYDR YVAICKPLHN TTIMTRHLCA MLVGVAWLGG FLHSLVQLLL VLWLPFCGPN VINHFACDLY PLLEVACTNT YVIGLLVVAN SGLICLLNFL MLAASYIVIL YSLRSHSADG RCKALSTCGA HFIVVALFFV PCIFTYVHPF STLPIDKNMA LFYGILTPML NPLIYTLRNE EVKNAMRKLF TW
Explore Olfactory receptor 4C3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets