About Olfactory receptor 4L1
Olfactory receptor 4L1 (OR4L1) is a protein
from Homo sapiens identified by UniProt accession
Q8NH43, 312 residues long.
MolForge cross-references it against 0 known binders and
6 disease associations.
Target properties
| Protein name | Olfactory receptor 4L1 |
|---|
| UniProt accession | Q8NH43 |
|---|
| Gene | OR4L1 |
|---|
| Organism | Homo sapiens |
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| Length | 312 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (6)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.24
- thyroid gland adenocarcinoma · score 0.22
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- metabolite measurement · score 0.10
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NH43-F1 | alphafold | PREDICTED | 85.45 | — |
Amino-acid sequence (312 residues)
MDLKNGSLVT EFILLGFFGR WELQIFFFVT FSLIYGATVM GNILIMVTVT CRSTLHSPLY FLLGNLSFLD MCLSTATTPK MIIDLLTDHK TISVWGCVTQ MFFMHFFGGA EMTLLIIMAF DRYVAICKPL HYRTIMSHKL LKGFAILSWI IGFLHSISQI VLTMNLPFCG HNVINNIFCD LPLVIKLACI ETYTLELFVI ADSGLLSFTC FILLLVSYIV ILVSVPKKSS HGLSKALSTL SAHIIVVTLF FGPCIFIYVW PFSSLASNKT LAVFYTVITP LLNPSIYTLR NKKMQEAIRK LRFQYVSSAQ NF
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