About Olfactory receptor 5B3
Olfactory receptor 5B3 (OR5B3) is a protein
from Homo sapiens identified by UniProt accession
Q8NH48, 314 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Olfactory receptor 5B3 |
|---|
| UniProt accession | Q8NH48 |
|---|
| Gene | OR5B3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 314 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.30
- neurodegenerative disease · score 0.28
- birth weight · score 0.24
- type 2 diabetes mellitus · score 0.24
- thyroid gland adenocarcinoma · score 0.22
- neuroblastoma · score 0.21
- prostate adenocarcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NH48-F1 | alphafold | PREDICTED | 86.45 | — |
Amino-acid sequence (314 residues)
MENKTEVTQF ILLGLTNDSE LQVPLFITFP FIYIITLVGN LGIIVLIFWD SCLHNPMYFF LSNLSLVDFC YSSAVTPIVM AGFLIEDKVI SYNACAAQMY IFVAFATVEN YLLASMAYDR YAAVCKPLHY TTTMTTTVCA RLAIGSYLCG FLNASIHTGD TFSLSFCKSN EVHHFFCDIP AVMVLSCSDR HISELVLIYV VSFNIFIALL VILISYTFIF ITILKMHSAS VYQKPLSTCA SHFIAVGIFY GTIIFMYLQP SSSHSMDTDK MAPVFYTMVI PMLNPLVYSL RNKEVKSAFK KVVEKAKLSV GWSV
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