About Olfactory receptor 4X1
Olfactory receptor 4X1 (OR4X1) is a protein
from Homo sapiens identified by UniProt accession
Q8NH49, 305 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Olfactory receptor 4X1 |
|---|
| UniProt accession | Q8NH49 |
|---|
| Gene | OR4X1 |
|---|
| Organism | Homo sapiens |
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| Length | 305 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (30)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- glomerular filtration rate · score 0.23
- thyroid gland adenocarcinoma · score 0.22
- low grade glioma · score 0.18
- pancreatic adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- chronic lymphocytic leukemia · score 0.18
- breast adenocarcinoma · score 0.18
- self reported educational attainment · score 0.11
- HbA1c measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NH49-F1 | alphafold | PREDICTED | 87.99 | — |
Amino-acid sequence (305 residues)
MVATNNVTEI IFVGFSQNWS EQRVISVMFL LMYTAVVLGN GLIVVTILAS KVLTSPMYFF LSYLSFVEIC YCSVMAPKLI FDSFIKRKVI SLKGCLTQMF SLHFFGGTEA FLLMVMAYDR YVAICKPLHY MAIMNQRMCG LLVRIAWGGG LLHSVGQTFL IFQLPFCGPN IMDHYFCDVH PVLELACADT FFISLLIITN GGSISVVSFF VLMASYLIIL HFLRSHNLEG QHKALSTCAS HVTVVDLFFI PCSLVYIRPC VTLPADKIVA VFYTVVTPLL NPVIYSFRNA EVKNAMRRFI GGKVI
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