About Olfactory receptor 8K5
Olfactory receptor 8K5 (OR8K5) is a protein
from Homo sapiens identified by UniProt accession
Q8NH50, 307 residues long.
MolForge cross-references it against 0 known binders and
6 disease associations.
Target properties
| Protein name | Olfactory receptor 8K5 |
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| UniProt accession | Q8NH50 |
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| Gene | OR8K5 |
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| Organism | Homo sapiens |
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| Length | 307 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (6)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- hepatocellular carcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- pancreatic adenocarcinoma · score 0.18
- leukocyte count · score 0.02
- high density lipoprotein cholesterol measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NH50-F1 | alphafold | PREDICTED | 89.44 | — |
Amino-acid sequence (307 residues)
MGQHNLTVLT EFILMELTRR PELQIPLFGV FLVIYLITVV GNLTMIILTK LDSHLHTPMY FSIRHLAFVD LGNSTVICPK VLANFVVDRN TISYYACAAQ LAFFLMFIIS EFFILSAMAY DRYVAICNPL LYYVIMSQRL CHVLVGIQYL YSTFQALMFT IKIFTLTFCG SNVISHFYCD DVPLLPMLCS NAQEIELLSI LFSVFNLISS FLIVLVSYML ILLAICQMHS AEGRKKAFST CGSHLTVVVV FYGSLLFMYM QPNSTHFFDT DKMASVFYTL VIPMLNPLIY SLRNEEVKNA FYKLFEN
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