About Olfactory receptor 8K3
Olfactory receptor 8K3 (OR8K3) is a protein
from Homo sapiens identified by UniProt accession
Q8NH51, 312 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Olfactory receptor 8K3 |
|---|
| UniProt accession | Q8NH51 |
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| Gene | OR8K3 |
|---|
| Organism | Homo sapiens |
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| Length | 312 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (11)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.19
- low grade glioma · score 0.18
- ovarian cancer · score 0.18
- prostate adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- Familial prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
- systolic blood pressure · score 0.04
- leukocyte count · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NH51-F1 | alphafold | PREDICTED | 89.32 | — |
Amino-acid sequence (312 residues)
MEQHNLTTVN EFILTGITDI AELQAPLFAL FLMIYVISVM GNLGMIVLTK LDSRLQTPMY FFLRHLAFMD LGYSTTVGPK MLVNFVVDKN IISYYFCATQ LAFFLVFIGS ELFILSAMSY DLYVAICNPL LYTVIMSRRV CQVLVAIPYL YCTFISLLVT IKIFTLSFCG YNVISHFYCD SLPLLPLLCS NTHEIELIIL IFAAIDLISS LLIVLLSYLL ILVAILRMNS AGRQKAFSTC GAHLTVVIVF YGTLLFMYVQ PKSSHSFDTD KVASIFYTLV IPMLNPLIYS LRNKDVKYAL RRTWNNLCNI FV
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