About Olfactory receptor 52J3
Olfactory receptor 52J3 (OR52J3) is a protein
from Homo sapiens identified by UniProt accession
Q8NH60, 311 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Olfactory receptor 52J3 |
| UniProt accession | Q8NH60 |
| Gene | OR52J3 |
| Organism | Homo sapiens |
| Length | 311 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- diet measurement · score 0.23
- sickle cell anemia · score 0.23
- chronic lymphocytic leukemia · score 0.18
- clear cell renal carcinoma · score 0.18
- hepatocellular carcinoma · score 0.18
- gastric carcinoma · score 0.00
- diabetes mellitus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q8NH60-F1 | alphafold | PREDICTED | 88.05 | — |
Amino-acid sequence (311 residues)
MFYHNKSIFH PVTFFLIGIP GLEDFHMWIS GPFCSVYLVA LLGNATILLV IKVEQTLREP MFYFLAILST IDLALSTTSV PRMLGIFWFD AHEINYGACV AQMFLIHAFT GMEAEVLLAM AFDRYVAVCA PLHYATILTS QVLVGISMCI VIRPVLLTLP MVYLIYRLPF CQAHIIAHSY CEHMGIAKLS CGNIRINGIY GLFVVSFFVL NLVLIGISYV YILRAVFRLP SHDAQLKALS TCGAHVGVIC VFYIPSVFSF LTHRFGHQIP GYIHILVANL YLIIPPSLNP IIYGVRTKQI RERVLYVFTK K
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