Olfactory receptor 5W2 (OR5W2)

About Olfactory receptor 5W2

Olfactory receptor 5W2 (OR5W2) is a protein from Homo sapiens identified by UniProt accession Q8NH69, 310 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein name	Olfactory receptor 5W2
UniProt accession	Q8NH69
Gene	OR5W2
Organism	Homo sapiens
Length	310 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (19)

Diseases linked to this target (Open Targets).

diastolic blood pressure · score 0.22
medulloblastoma · score 0.21
clear cell renal carcinoma · score 0.18
prostate adenocarcinoma · score 0.18
ovarian cancer · score 0.18
pancreatic adenocarcinoma · score 0.18
breast adenocarcinoma · score 0.18
apolipoprotein A 1 measurement · score 0.16
high density lipoprotein cholesterol measurement · score 0.15
C-reactive protein measurement · score 0.15

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NH69-F1	alphafold	PREDICTED	91.05	—

Amino-acid sequence (310 residues)

MDWENCSSLT DFFLLGITNN PEMKVTLFAV FLAVYIINFS ANLGMIVLIR MDYQLHTPMY FFLSHLSFCD LCYSTATGPK MLVDLLAKNK SIPFYGCALQ FLVFCIFADS ECLLLSVMAF DRYKAIINPL LYTVNMSSRV CYLLLTGVYL VGIADALIHM TLAFRLCFCG SNEINHFFCD IPPLLLLSRS DTQVNELVLF TVFGFIELST ISGVFISYCY IILSVLEIHS AEGRFKALST CTSHLSAVAI FQGTLLFMYF RPSSSYSLDQ DKMTSLFYTL VVPMLNPLIY SLRNKDVKEA LKKLKNKILF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards