Olfactory receptor 5AK2 (OR5AK2)

About Olfactory receptor 5AK2

Olfactory receptor 5AK2 (OR5AK2) is a protein from Homo sapiens identified by UniProt accession Q8NH90, 309 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein name	Olfactory receptor 5AK2
UniProt accession	Q8NH90
Gene	OR5AK2
Organism	Homo sapiens
Length	309 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (19)

Diseases linked to this target (Open Targets).

reticulocyte count · score 0.24
thyroid gland adenocarcinoma · score 0.22
gut microbiome measurement · score 0.22
ovarian cancer · score 0.18
prostate adenocarcinoma · score 0.18
breast adenocarcinoma · score 0.18
smoking behaviour measurement · score 0.12
unipolar depression · score 0.12
neurofibrillary tangles measurement · score 0.10
small bowel Crohn's disease · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NH90-F1	alphafold	PREDICTED	84.25	—

Amino-acid sequence (309 residues)

MTLGNSTEVT EFYLLGFGAQ HEFWCILFIV FLLIYVTSIM GNSGIILLIN TDSRFQTLTY FFLQHLAFVD ICYTSAITPK MLQSFTEEKN LMLFQGCVIQ FLVYATFATS DCYLLAMMAV DPYVAICKPL HYTVIMSRTV CIRLVAGSYI MGSINASVQT GFTCSLSFCK SNSINHFFCD VPPILALSCS NVDINIMLLV VFVGSNLIFT GLVVIFSYIY IMATILKMSS SAGRKKSFST CASHLTAVTI FYGTLSYMYL QSHSNNSQEN MKVAFIFYGT VIPMLNPLIY SLRNKEVKEA LKVIGKKLF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards