About Olfactory receptor 2V1
Olfactory receptor 2V1 (OR2V1) is a protein
from Homo sapiens identified by UniProt accession
Q8NHB1, 315 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Olfactory receptor 2V1 |
|---|
| UniProt accession | Q8NHB1 |
|---|
| Gene | OR2V1 |
|---|
| Organism | Homo sapiens |
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| Length | 315 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (7)
Diseases linked to this target (Open Targets).
- medulloblastoma · score 0.21
- breast adenocarcinoma · score 0.18
- breast carcinoma · score 0.04
- colorectal adenocarcinoma · score 0.04
- pancreatic adenocarcinoma · score 0.04
- carcinoma of liver and intrahepatic biliary tract · score 0.03
- blood protein measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NHB1-F1 | alphafold | PREDICTED | 86.06 | — |
Amino-acid sequence (315 residues)
MGRWVNQSYT DGFFLLGIFS HSQTDLVLFS AVMVVFTVAL CGNVLLIFLI YLDAGLHTPM YFFLSQLSLM DLMLVCNIVP KMAANFLSGR KSISFVGCGI QIGFFVSLVG SEGLLLGLMA YDRYVAVSHP LHYPILMNQR VCLQITGSSW AFGIIDGVIQ MVAAMGLPYC GSRSVDHFFC EVQALLKLAC ADTSLFDTLL FACCVFMLLL PFSIIMASYA CILGAVLRIR SAQAWKKALA TCSSHLTAVT LFYGAAMFMY LRPRRYRAPS HDKVASIFYT VLTPMLNPLI YSLRNGEVMG ALRKGLDRCR IGSQH
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