About Olfactory receptor 10J5
Olfactory receptor 10J5 (OR10J5) is a protein
from Homo sapiens identified by UniProt accession
Q8NHC4, 309 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Olfactory receptor 10J5 |
| UniProt accession | Q8NHC4 |
| Gene | OR10J5 |
| Organism | Homo sapiens |
| Length | 309 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- growth-regulated alpha protein measurement · score 0.22
- low grade glioma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- C-reactive protein measurement · score 0.16
- blood phosphate measurement · score 0.12
- metabolite measurement · score 0.03
- CCL2 measurement · score 0.02
- Hepatic steatosis · score 0.01
- muscular dystrophy · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q8NHC4-F1 | alphafold | PREDICTED | 86.21 | — |
Amino-acid sequence (309 residues)
MKRKNFTEVS EFIFLGFSSF GKHQITLFVV FLTVYILTLV ANIIIVTIIC IDHHLHTPMY FFLSMLASSE TVYTLVIVPR MLLSLIFHNQ PISLAGCATQ MFFFVILATN NCFLLTAMGY DRYVAICRPL RYTVIMSKGL CAQLVCGSFG IGLTMAVLHV TAMFNLPFCG TVVDHFFCDI YPVMKLSCID TTINEIINYG VSSFVIFVPI GLIFISYVLV ISSILQIASA EGRKKTFATC VSHLTVVIVH CGCASIAYLK PKSESSIEKD LVLSVTYTII TPLLNPVVYS LRNKEVKDAL CRVVGRNIS
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