About Olfactory receptor 14A16
Olfactory receptor 14A16 (OR14A16) is a protein
from Homo sapiens identified by UniProt accession
Q8NHC5, 309 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Olfactory receptor 14A16 |
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| UniProt accession | Q8NHC5 |
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| Gene | OR14A16 |
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| Organism | Homo sapiens |
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| Length | 309 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (16)
Diseases linked to this target (Open Targets).
- platelet crit · score 0.23
- neuroblastoma · score 0.21
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- multiple myeloma · score 0.16
- reticulocyte count · score 0.15
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
- Familial prostate cancer · score 0.11
- diffuse large B-cell lymphoma · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NHC5-F1 | alphafold | PREDICTED | 89.01 | — |
Amino-acid sequence (309 residues)
MANLTIVTEF ILMGFSTNKN MCILHSILFL LIYLCALMGN VLIIMITTLD HHLHTPVYFF LKNLSFLDLC LISVTAPKSI ANSLIHNNSI SFLGCVSQVF LLLSSASAEL LLLTVMSFDR YTAICHPLHY DVIMDRSTCV QRATVSWLYG GLIAVMHTAG TFSLSYCGSN MVHQFFCDIP QLLAISCSEN LIREIALILI NVVLDFCCFI VIIITYVHVF STVKKIPSTE GQSKAYSICL PHLLVVLFLS TGFIAYLKPA SESPSILDAV ISVFYTMLPP TFNPIIYSLR NKAIKVALGM LIKGKLTKK
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