About Olfactory receptor 2T6
Olfactory receptor 2T6 (OR2T6) is a protein
from Homo sapiens identified by UniProt accession
Q8NHC8, 308 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Olfactory receptor 2T6 |
|---|
| UniProt accession | Q8NHC8 |
|---|
| Gene | OR2T6 |
|---|
| Organism | Homo sapiens |
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| Length | 308 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (12)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- diffuse large B-cell lymphoma · score 0.10
- cancer · score 0.01
- neoplasm · score 0.01
- autism · score 0.01
- lymph node metastatic carcinoma · score 0.01
- Hyperlipidemia · score 0.00
- neuropathy · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NHC8-F1 | alphafold | PREDICTED | 88.27 | — |
Amino-acid sequence (308 residues)
MNENNETLTR GFTLMGLFTH NKCSGFFFGV ICAVFFMAMI ANGVMIFLIN IDPHLHTPMY FLLSHLSVID TLYISTIVPK MLVDYLMGEG TISFIACTAQ CFLYMGFMGA EFFLLGLMAY DRYVAICNPL RYPVLISWRV CWMILASSWF GGALDSFLLT PITMSLPFCA SHQINHFFCE APTMLRLACG DKTTYETVMY VCCVAMLLIP FSVVTASYTR ILITVHQMTS AEGRKKAFAT CSSHMMVVTL FYGAALYTYT LPQSYHTPIK DKVFSAFYTI LTPLLNPLIY SLRNRDVMGA LKRVVARC
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