Small VCP/p97-interacting protein (SVIP)

About Small VCP/p97-interacting protein

Small VCP/p97-interacting protein (SVIP) is a protein from Homo sapiens identified by UniProt accession Q8NHG7, 77 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Small VCP/p97-interacting protein
UniProt accession	Q8NHG7
Gene	SVIP
Organism	Homo sapiens
Length	77 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

lymphocyte count · score 0.10
neoplasm · score 0.06
cancer · score 0.04
Hepatic fibrosis · score 0.04
mucocutaneous lymph node syndrome · score 0.03
immature platelet fraction · score 0.03
diastolic blood pressure · score 0.03
systolic blood pressure · score 0.03
mean arterial pressure · score 0.03
platelet count · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NHG7-F1	alphafold	PREDICTED	71.11	—

Amino-acid sequence (77 residues)

MGLCFPCPGE SAPPTPDLEE KRAKLAEAAE RRQKEAASRG ILDVQSVQEK RKKKEKIEKQ IATSGPPPEG GLRWTVS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards