Killer cell immunoglobulin-like receptor 2DL5B (KIR2DL5B)

Homo sapiens — UniProt Q8NHK3

Gene: KIR2DL5BHomo sapiensSwissProt reviewed

About Killer cell immunoglobulin-like receptor 2DL5B

Killer cell immunoglobulin-like receptor 2DL5B (KIR2DL5B) is a protein from Homo sapiens identified by UniProt accession Q8NHK3, 375 residues long. MolForge cross-references it against 0 known binders and 0 disease associations.

Target properties

Protein nameKiller cell immunoglobulin-like receptor 2DL5B
UniProt accessionQ8NHK3
GeneKIR2DL5B
OrganismHomo sapiens
Length375 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8NHK3-F1alphafoldPREDICTED72.03—

Amino-acid sequence (375 residues)

MSLMVVSMAC VGFFLLQGAW THEGGQDKPL LSAWPSAVVP RGGHVTLLCR SRLGFTIFSL YKEDGVPVPE LYNKIFWKSI LMGPVTPAHA GTYRCRGSHP RSPIEWSAPS NPLVIVVTGL FGKPSLSAQP GPTVRTGENV TLSCSSRSSF DMYHLSREGR AHEPRLPAVP SVDGTFQADF PLGPATHGGT YTCFSSLHDS PYEWSDPSDP LLVSVTGNSS SSSSSPTEPS SKTGIRRHLH ILIGTSVAII LFIILFFFLL HCCCSNKKNA AVMDQEPAGD RTVNREDSDD QDPQEVTYAQ LDHCVFTQTK ITSPSQRPKT PPTDTTMYME LPNAKPRSLS PAHKHHSQAL RGSSRETTAL SQNRVASSHV PAAGI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Explore Killer cell immunoglobulin-like receptor 2DL5B with MolForge

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Quick facts

UniProtQ8NHK3
GeneKIR2DL5B
OrganismHomo sapiens
Length375
Binders0
Diseases0
View on UniProt