Putative aspartate aminotransferase, cytoplasmic 2 (GOT1L1)

About Putative aspartate aminotransferase, cytoplasmic 2

Putative aspartate aminotransferase, cytoplasmic 2 (GOT1L1) is a protein from Homo sapiens identified by UniProt accession Q8NHS2, 421 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.

Target properties

Protein name	Putative aspartate aminotransferase, cytoplasmic 2
UniProt accession	Q8NHS2
Gene	GOT1L1
Organism	Homo sapiens
Length	421 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NHS2-F1	alphafold	PREDICTED	91.90	—

Amino-acid sequence (421 residues)

MPTLSVFMDV PLAHKLEGSL LKTYKQDDYP NKIFLAYRVC MTNEGHPWVS LVVQKTRLQI SQDPSLNYEY LPTMGLKSFI QASLALLFGK HSQAIVENRV GGVHTVGDSG AFQLGVQFLR AWHKDARIVY IISSQKELHG LVFQDMGFTV YEYSVWDPKK LCMDPDILLN VVEQIPHGCV LVMGNIIDCK LTPSGWAKLM SMIKSKQIFP FFDIPCQGLY TSDLEEDTRI LQYFVSQGFE FFCSQSLSKN FGIYDEGVGM LVVVAVNNQQ LLCVLSQLEG LAQALWLNPP NTGARVITSI LCNPALLGEW KQSLKEVVEN IMLTKEKVKE KLQLLGTPGS WGHITEQSGT HGYLGLNSQQ VEYLVRKKHI YIPKNGQINF SCINANNINY ITEGINEAVL LTESSEMCLP KEKKTLIGIK L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards