GTPase IMAP family member 7 (GIMAP7)

About GTPase IMAP family member 7

GTPase IMAP family member 7 (GIMAP7) is a protein from Homo sapiens identified by UniProt accession Q8NHV1, 300 residues long. MolForge cross-references it against 0 known binders and 146 disease associations.

Target properties

Protein name	GTPase IMAP family member 7
UniProt accession	Q8NHV1
Gene	GIMAP7
Organism	Homo sapiens
Length	300 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (146)

Diseases linked to this target (Open Targets).

lymphocyte count · score 0.36
reticulocyte count · score 0.36
lymphocyte percentage of leukocytes · score 0.29
neutrophil percentage of leukocytes · score 0.29
triglyceride measurement · score 0.28
mean platelet volume · score 0.27
red blood cell density measurement · score 0.26
high density lipoprotein cholesterol measurement · score 0.26
eosinophil count · score 0.22
apolipoprotein A 1 measurement · score 0.22

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NHV1-F1	alphafold	PREDICTED	92.72	—

Amino-acid sequence (300 residues)

MAESEDRSLR IVLVGKTGSG KSATANTILG EEIFDSRIAA QAVTKNCQKA SREWQGRDLL VVDTPGLFDT KESLDTTCKE ISRCIISSCP GPHAIVLVLL LGRYTEEEQK TVALIKAVFG KSAMKHMVIL FTRKEELEGQ SFHDFIADAD VGLKSIVKEC GNRCCAFSNS KKTSKAEKES QVQELVELIE KMVQCNEGAY FSDDIYKDTE ERLKQREEVL RKIYTDQLNE EIKLVEEDKH KSEEEKEKEI KLLKLKYDEK IKNIREEAER NIFKDVFNRI WKMLSEIWHR FLSKCKFYSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards