C-C motif chemokine 4-like (CCL4L1)

About C-C motif chemokine 4-like

C-C motif chemokine 4-like (CCL4L1) is a protein from Homo sapiens identified by UniProt accession Q8NHW4, 92 residues long. MolForge cross-references it against 0 known binders and 193 disease associations.

Target properties

Protein name	C-C motif chemokine 4-like
UniProt accession	Q8NHW4
Gene	CCL4L1
Organism	Homo sapiens
Length	92 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (193)

Diseases linked to this target (Open Targets).

Hashimoto's thyroiditis · score 0.05
autoimmune disease · score 0.05
blood protein measurement · score 0.05
autosomal systemic lupus erythematosus type 16 · score 0.05
C1 inhibitor deficiency · score 0.05
pemphigus vulgaris · score 0.04
complement component C1s deficiency · score 0.04
immunodeficiency due to MASP-2 deficiency · score 0.04
CCL4 measurement · score 0.04
C1Q deficiency 1 · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NHW4-F1	alphafold	PREDICTED	89.02	—

Amino-acid sequence (92 residues)

MKLCVTVLSL LVLVAAFCSL ALSAPMGSDP PTACCFSYTA RKLPRNFVVD YYETSSLCSQ PAVVFQTKRG KQVCADPSES WVQEYVYDLE LN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards