Anaphase-promoting complex subunit CDC26 (CDC26)

About Anaphase-promoting complex subunit CDC26

Anaphase-promoting complex subunit CDC26 (CDC26) is a protein from Homo sapiens identified by UniProt accession Q8NHZ8, 85 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Anaphase-promoting complex subunit CDC26
UniProt accession	Q8NHZ8
Gene	CDC26
Organism	Homo sapiens
Length	85 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (23)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
reticulocyte count · score 0.14
esophageal cancer · score 0.13
reticulocyte measurement · score 0.12
appendicular lean mass · score 0.12
mean corpuscular hemoglobin · score 0.09
neutrophil count · score 0.06
body fat percentage · score 0.05
mean corpuscular volume · score 0.05
leukocyte count · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NHZ8-F1	alphafold	PREDICTED	72.99	—

Amino-acid sequence (85 residues)

MLRRKPTRLE LKLDDIEEFE NIRKDLETRK KQKEDVEVVG GSDGEGAIGL SSDPKSREQM INDRIGYKPQ PKPNNRSSQF GSLEF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards