About Protein phosphatase PTC7 homolog
Protein phosphatase PTC7 homolog (PPTC7) is a protein
from Homo sapiens identified by UniProt accession
Q8NI37, 304 residues long.
MolForge cross-references it against 0 known binders and
50 disease associations.
Target properties
| Protein name | Protein phosphatase PTC7 homolog |
|---|
| UniProt accession | Q8NI37 |
|---|
| Gene | PPTC7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 304 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (50)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- cystatin C measurement · score 0.20
- neuroinflammatory disorder · score 0.18
- erythrocyte count · score 0.08
- peak expiratory flow · score 0.06
- body mass index · score 0.05
- hemoglobin measurement · score 0.05
- blood protein measurement · score 0.04
- Headache · score 0.04
- schizophrenia · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NI37-F1 | alphafold | PREDICTED | 88.39 | — |
Amino-acid sequence (304 residues)
MFSVLSYGRL VARAVLGGLS QTDPRAGGGG GGDYGLVTAG CGFGKDFRKG LLKKGACYGD DACFVARHRS ADVLGVADGV GGWRDYGVDP SQFSGTLMRT CERLVKEGRF VPSNPIGILT TSYCELLQNK VPLLGSSTAC IVVLDRTSHR LHTANLGDSG FLVVRGGEVV HRSDEQQHYF NTPFQLSIAP PEAEGVVLSD SPDAADSTSF DVQLGDIILT ATDGLFDNMP DYMILQELKK LKNSNYESIQ QTARSIAEQA HELAYDPNYM SPFAQFACDN GLNVRGGKPD DITVLLSIVA EYTD
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