About Retinitis pigmentosa 9 protein
Retinitis pigmentosa 9 protein (RP9) is a protein
from Homo sapiens identified by UniProt accession
Q8TA86, 221 residues long.
MolForge cross-references it against 0 known binders and
43 disease associations.
Target properties
| Protein name | Retinitis pigmentosa 9 protein |
|---|
| UniProt accession | Q8TA86 |
|---|
| Gene | RP9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 221 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (43)
Diseases linked to this target (Open Targets).
- retinitis pigmentosa · score 0.64
- autosomal dominant retinitis pigmentosa · score 0.37
- neurodegenerative disease · score 0.31
- Red cell distribution width · score 0.29
- body height · score 0.27
- Retinal dystrophy · score 0.18
- brain measurement · score 0.10
- cortical surface area measurement · score 0.09
- neuroimaging measurement · score 0.09
- cortical thickness · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TA86-F1 | alphafold | PREDICTED | 77.73 | — |
Amino-acid sequence (221 residues)
MSSRPGREDV GAAGARRPRE PPEQELQRRR EQKRRRHDAQ QLQQLKHLES FYEKPPPGLI KEDETKPEDC IPDVPGNEHA REFLAHAPTK GLWMPLGKEV KVMQCWRCKR YGHRTGDKEC PFFIKGNQKL EQFRVAHEDP MYDIIRDNKR HEKDVRIQQL KQLLEDSTSD EDRSSSSSSE GKEKHKKKKK KEKHKKRKKE KKKKKKRKHK SSKSNEGSDS E
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