About UPF0500 protein C1orf216
UPF0500 protein C1orf216 (C1orf216) is a protein
from Homo sapiens identified by UniProt accession
Q8TAB5, 229 residues long.
MolForge cross-references it against 0 known binders and
19 disease associations.
Target properties
| Protein name | UPF0500 protein C1orf216 |
|---|
| UniProt accession | Q8TAB5 |
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| Gene | C1orf216 |
|---|
| Organism | Homo sapiens |
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| Length | 229 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (19)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.27
- protein measurement · score 0.23
- type 1 diabetes mellitus · score 0.09
- schizophrenia · score 0.07
- BMI-adjusted waist circumference · score 0.06
- mean reticulocyte volume · score 0.03
- mean corpuscular volume · score 0.03
- ependymoma · score 0.02
- systemic juvenile idiopathic arthritis · score 0.01
- oligodendroglioma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TAB5-F1 | alphafold | PREDICTED | 66.20 | — |
Amino-acid sequence (229 residues)
MFAIQPGLAE GGQFLGDPPP GLCQPELQPD SNSNFMASAK DANENWHGMP GRVEPILRRS SSESPSDNQA FQAPGSPEEG VRSPPEGAEI PGAEPEKMGG AGTVCSPLED NGYASSSLSI DSRSSSPEPA CGTPRGPGPP DPLLPSVAQA VQHLQVQERY KEQEKEKHHV HLVMYRRLAL LQWIRGLQHQ LIDQQARLQE SFDTILDNRK ELIRCLQQRA APSRPQDQA
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