Rieske domain-containing protein (RFESD)

About Rieske domain-containing protein

Rieske domain-containing protein (RFESD) is a protein from Homo sapiens identified by UniProt accession Q8TAC1, 157 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein name	Rieske domain-containing protein
UniProt accession	Q8TAC1
Gene	RFESD
Organism	Homo sapiens
Length	157 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (7)

Diseases linked to this target (Open Targets).

metabolite measurement · score 0.06
FEV/FVC ratio · score 0.04
osteosarcoma · score 0.02
drug use measurement · score 0.02
hepatocellular carcinoma · score 0.00
myelodysplastic syndrome · score 0.00
acute myeloid leukemia · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8TAC1-F1	alphafold	PREDICTED	90.76	—

Amino-acid sequence (157 residues)

MNLDGSAQDP EKREYSSVCV GREDDIKKSE RMTAVVHDRE VVIFYHKGEY HAMDIRCYHS GGPLHLGDIE DFDGRPCIVC PWHKYKITLA TGEGLYQSIN PKDPSAKPKW CSKGIKQRIH TVTVDNGNIY VTLSNEPFKC DSDFYATGDF KVIKSSS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards