About Secretory carrier-associated membrane protein 5
Secretory carrier-associated membrane protein 5 (SCAMP5) is a protein
from Homo sapiens identified by UniProt accession
Q8TAC9, 235 residues long.
MolForge cross-references it against 0 known binders and
65 disease associations.
Target properties
| Protein name | Secretory carrier-associated membrane protein 5 |
|---|
| UniProt accession | Q8TAC9 |
|---|
| Gene | SCAMP5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 235 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (65)
Diseases linked to this target (Open Targets).
- Global developmental delay · score 0.53
- Intellectual disability · score 0.46
- Atypical behavior · score 0.46
- Seizure · score 0.46
- genetic disorder · score 0.40
- smoking status measurement · score 0.39
- diastolic blood pressure · score 0.37
- systolic blood pressure · score 0.36
- neurodegenerative disease · score 0.36
- alcohol drinking · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8TAC9-F1 | alphafold | PREDICTED | 86.38 | — |
Amino-acid sequence (235 residues)
MAEKVNNFPP LPKFIPLKPC FYQDFEADIP PQHVSMTKRL YYLWMLNSVT LAVNLVGCLA WLIGGGGATN FGLAFLWLIL FTPCSYVCWF RPIYKAFKTD SSFSFMAFFF TFMAQLVISI IQAVGIPGWG VCGWIATISF FGTNIGSAVV MLIPTVMFTV MAVFSFIALS MVHKFYRGSG GSFSKAQEEW TTGAWKNPHV QQAAQNAAMG AAQGAMNQPQ TQYSATPNYT YSNEM
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